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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDH2
All Species:
31.82
Human Site:
S74
Identified Species:
77.78
UniProt:
P19022
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19022
NP_001783.2
906
99809
S74
R
K
V
Q
Y
E
S
S
E
P
A
D
F
K
V
Chimpanzee
Pan troglodytes
XP_523898
1236
135068
S405
R
K
V
Q
Y
E
S
S
E
P
A
D
F
K
V
Rhesus Macaque
Macaca mulatta
XP_001100341
916
101235
S84
R
K
V
Q
Y
E
S
S
E
P
A
D
F
K
V
Dog
Lupus familis
XP_537293
1074
118057
S242
R
K
V
Q
Y
E
S
S
E
P
A
D
F
K
V
Cat
Felis silvestris
Mouse
Mus musculus
P15116
906
99743
S74
R
K
V
Q
Y
E
S
S
E
P
A
D
F
K
V
Rat
Rattus norvegicus
Q9Z1Y3
906
99668
S74
R
K
V
Q
Y
E
S
S
E
P
A
D
F
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515514
902
99677
G76
D
F
R
V
D
E
D
G
V
V
Y
A
A
R
G
Chicken
Gallus gallus
P10288
912
100446
S79
R
K
I
Y
F
G
S
S
E
P
E
D
F
R
V
Frog
Xenopus laevis
P33147
906
100375
S77
R
R
I
H
Y
E
T
S
N
P
T
D
F
R
I
Zebra Danio
Brachydanio rerio
Q90275
893
98972
T81
F
R
I
D
A
D
G
T
V
M
A
A
R
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73
96.6
83.1
N.A.
96.2
96.2
N.A.
90.4
85.6
80.2
71.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
73.1
97.4
83.8
N.A.
97.6
97.9
N.A.
94.6
92.6
88.1
83.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
60
46.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
80
80
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
0
70
20
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
10
10
10
10
0
0
0
0
80
0
0
0
% D
% Glu:
0
0
0
0
0
80
0
0
70
0
10
0
0
0
0
% E
% Phe:
10
10
0
0
10
0
0
0
0
0
0
0
80
0
0
% F
% Gly:
0
0
0
0
0
10
10
10
0
0
0
0
0
0
10
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
30
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
70
0
0
0
0
0
0
0
0
0
0
0
60
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
80
0
0
0
0
0
% P
% Gln:
0
0
0
60
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
80
20
10
0
0
0
0
0
0
0
0
0
10
30
0
% R
% Ser:
0
0
0
0
0
0
70
80
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
10
10
0
0
10
0
0
10
0
% T
% Val:
0
0
60
10
0
0
0
0
20
10
0
0
0
0
70
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
70
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _